Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 5/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804313 | 0.94 | CXCR2 (0.38) | CXCR2IDO1TDO2CRHBPCRHR2 | |
| SCHEMBL7780384 | 0.87 | CXCR2 (0.33) | CXCR2MAPKAPK2 | |
| SCHEMBL7795456 | 0.85 | CXCR2 (0.35) | CXCR2GAAALDH1A1 | |
| SCHEMBL7787494 | 0.81 | KMT2A (0.38) | CXCR2CRHBPCRHR2GAAMAPT | |
| Hydrochloric Acid SCHEMBL7801938 | 0.81 | CXCR2 (0.35) | CXCR2GAAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7785125 | 0.81 | CXCR2 (0.32) | CXCR2 | |
| SCHEMBL7801984 | 0.81 | CXCR2 (0.36) | CXCR2IDO1MAPTMAPKAPK2MEN1 | |
| SCHEMBL7805393 | 0.79 | CXCR2 (0.40) | CXCR2MAPKAPK2MEN1KMT2A | |
| SCHEMBL7795412 | 0.79 | CXCR2 (0.40) | CXCR2MAPKAPK2MEN1KMT2A | |
| SCHEMBL7789230 | 0.79 | KMT2A (0.36) | CXCR2CRHBPCRHR2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |