Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | CASR | P41180 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787494 | 0.92 | KMT2A (0.38) | KMT2AMAPTMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL7789132 | 0.90 | CRHBP (0.39) | KMT2AMAPTMEN1CRHBPCRHR2 | |
| SCHEMBL7785066 | 0.83 | CRHBP (0.39) | KMT2AMAPTMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL7785112 | 0.81 | KMT2A (0.44) | KMT2AMAPTMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL7795386 | 0.79 | CXCR2 (0.39) | KMT2AMAPTMEN1SMN1; SMN2CRHBP | |
| SCHEMBL7785589 | 0.78 | MAPKAPK2 (0.45) | MAPK1MAPKAPK2 | |
| SCHEMBL7780384 | 0.77 | CXCR2 (0.33) | MAPKAPK2CXCR2 | |
| SCHEMBL7785272 | 0.75 | KMT2A (0.41) | KMT2AMAPTMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL7785111 | 0.75 | CASR (0.45) | KMT2AMAPTMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL7795456 | 0.75 | CXCR2 (0.35) | ALDH1A1GAALMNACXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |