Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795386 | 0.94 | CXCR2 (0.39) | CXCR2GAAMEN1MAPTKMT2A | |
| SCHEMBL7795456 | 0.90 | CXCR2 (0.35) | CXCR2GAATHRATHRBADRB3 | |
| Hydrochloric Acid SCHEMBL7801938 | 0.88 | CXCR2 (0.35) | CXCR2GAAMAPTKMT2ATHRA | |
| SCHEMBL7785125 | 0.87 | CXCR2 (0.32) | CXCR2 | |
| SCHEMBL7801234 | 0.81 | THRA (0.36) | CXCR2GAAMEN1MAPTKMT2A | |
| SCHEMBL7780576 | 0.81 | KMT2A (0.40) | CXCR2GAAMEN1KMT2ATHRA | |
| SCHEMBL7795354 | 0.81 | KMT2A (0.40) | CXCR2GAAMEN1KMT2ATHRA | |
| SCHEMBL7802013 | 0.81 | KMT2A (0.40) | CXCR2GAAMEN1KMT2ATHRA | |
| SCHEMBL7780384 | 0.81 | CXCR2 (0.33) | CXCR2 | |
| Hydrochloric Acid SCHEMBL7801297 | 0.80 | KMT2A (0.40) | CXCR2GAAMEN1KMT2ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |