Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10065533 | 1.00 | TRPV1 (0.71) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17335640 | 0.87 | TRPV1 (0.55) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28400950 | 0.86 | TRPV1 (0.66) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL57332 | 0.84 | TRPV1 (0.59) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4558356 | 0.84 | TRPV1 (0.59) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4558360 | 0.84 | TRPV1 (0.59) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8834742 | 0.83 | TRPV1 (0.72) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27704907 | 0.81 | CYP1A2 (0.57) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL679954 | 0.81 | CYP1A2 (1.00) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1155739 | 0.81 | CYP1A2 (1.00) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835233-B1 | COMPOSITION AND METHOD FOR STABILIZING RADIOLABELED ORGANIC COMPOUNDS | NEN LIFE SCIENCE PROD INC (US) | 2001-12-05 | — | — | EP | disclosed |
| US-5843396-A | Method for stabilizing radiolabeled organic compounds by adding a separate stabilizing compound | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 1998-12-01 | — | — | US | disclosed |
| US-5738836-A | Composition for stabilizing radiolabeled organic compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| US-4411881-A | Composition and method for stabilizing radiolabeled compounds using thiocarbonylated diethylenetriamines | NEW ENGLAND NUCLEAR CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |