SCHEMBL10065533

SCHEMBL10065533

CCCCCCC(C)C(=O)NCc1ccc(O)c(OC)c1

nearest known ligand 0.71

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 7/20 0.71
CYP1A2 P05177 2/20 0.67
CYP3A4 P08684 2/20 0.67
CYP2D6 P10635 2/20 0.67
CYP2C9 P11712 2/20 0.67
CYP2C19 P33261 2/20 0.67
BLM P54132 2/20 0.67
PMP22 Q01453 2/20 0.67
ALDH1A1 P00352 1/20 0.67
HPGD P15428 1/20 0.67
ALOX15 P16050 1/20 0.67
MEN1 O00255 1/20 0.64
POLB P06746 1/20 0.64
TSHR P16473 1/20 0.64
KMT2A Q03164 1/20 0.64
NPSR1 Q6W5P4 1/20 0.64
HTR1A P08908 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7795391 1.00 TRPV1 (0.71) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL17335640 0.87 TRPV1 (0.55) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL28400950 0.86 TRPV1 (0.66) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL57332 0.84 TRPV1 (0.59) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL4558356 0.84 TRPV1 (0.59) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL4558360 0.84 TRPV1 (0.59) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL8834742 0.83 TRPV1 (0.72) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL27704907 0.81 CYP1A2 (0.57) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL679954 0.81 CYP1A2 (1.00) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL1155739 0.81 CYP1A2 (1.00) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120089105-A1 SELF-ADHESIVE SKIN PATCH AND COMBINATION SET FOR COSMETIC SKIN CARE BEIERSDORF AG (DE) 2012-04-12 US disclosed
US-8101216-B2 Self-adhesive skin patch and combination set for cosmetic skin care BEIERSDORF AG (DE) 2012-01-24 US disclosed
US-7993654-B2 Self-adhesive polymer matrix containing sea algae extract BEIERSDORF AG (DE) 2011-08-09 US disclosed
US-20110076321-A1 SELF-ADHESIVE POLYMER MATRIX CONTAINING SEA ALGAE EXTRACT BEIERSDORF AG (DE) 2011-03-31 US disclosed
US-7829099-B2 Self-adhesive polymer matrix containing sea algae extract and glycerin BEIERSDORF AG (DE) 2010-11-09 US disclosed
US-7820177-B2 Self-adhesive polymer matrix containing a seaweed extract BEIERSDORF AG (DE) 2010-10-26 US disclosed
US-7767224-B2 Method for the continuous production and coating of self-adhesive compounds on the basis of SBC that includes at least one pharmaceutically active substance BEIERSDORF AG (DE) 2010-08-03 US disclosed
US-20080038300-A1 Self-Adhesive Skin Patch and Combination Set for Cosmetic Skin Care BEIERSDORF AG (DE) 2008-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120089105-A1 SELF-ADHESIVE SKIN PATCH AND COMBINATION SET FOR COSMETIC SKIN CARE CUTA, CTCF, LAGE3 TRPV1 2418/4885CYP1A2 4843/4885CYP3A4 4857/4885
US-20080038300-A1 Self-Adhesive Skin Patch and Combination Set for Cosmetic Skin Care CUTA, CTCF, LAGE3 TRPV1 2418/4885CYP1A2 4843/4885CYP3A4 4857/4885
US-20110076321-A1 SELF-ADHESIVE POLYMER MATRIX CONTAINING SEA ALGAE EXTRACT EPCAM, ICAM1, ALG1 TRPV1 2995/4885CYP1A2 4410/4885CYP3A4 4762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.