Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10065533 | 0.86 | TRPV1 (0.71) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7795391 | 0.86 | TRPV1 (0.71) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5047559 | 0.85 | HTR1A (0.60) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22462684 | 0.85 | HTR1A (0.60) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5047574 | 0.85 | HTR1A (0.60) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5051127 | 0.85 | HTR1A (0.60) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL299310 | 0.84 | HTR1A (0.59) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29370506 | 0.84 | HTR1A (0.59) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29549298 | 0.84 | HTR1A (0.59) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1286871 | 0.84 | HTR1A (0.59) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110168038-B | Methyl menthol derivative and cold sensate composition containing same | 高砂香料工业株式会社 | 2022-05-27 | — | — | CN | claimed |
| CN-111212884-A | Cold-sensitive composition containing 2,2, 6-trimethylcyclohexanecarboxylic acid derivative | 高砂香料工业株式会社 | 2020-05-29 | — | — | CN | claimed |
| CN-110168038-B | Methyl menthol derivative and cold sensate composition containing same | 高砂香料工业株式会社 | 2022-05-27 | — | — | CN | disclosed |
| CN-111212884-A | Cold-sensitive composition containing 2,2, 6-trimethylcyclohexanecarboxylic acid derivative | 高砂香料工业株式会社 | 2020-05-29 | — | — | CN | disclosed |