Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.56 |
| ▸ | ERN1 | O75460 | 3/20 | 0.53 |
| ▸ | NSD2 | O96028 | 3/20 | 0.52 |
| ▸ | CASP6 | P55212 | 4/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26891719 | 0.85 | CASP6 (0.63) | NT5EERN1NSD2CASP6DUSP3 | |
| SCHEMBL6568796 | 0.82 | CASP6 (0.78) | NT5ENSD2CASP6DUSP3PTPN5 | |
| SCHEMBL26885948 | 0.79 | NT5E (0.68) | NT5ENSD2CASP6DUSP3PTPN5 | |
| SCHEMBL8109724 | 0.78 | NT5E (0.74) | NT5ENSD2CASP6DUSP3PTPN5 | |
| SCHEMBL8574929 | 0.75 | PRMT1 (0.64) | NT5ENSD2CASP6DUSP3PTPN5 | |
| SCHEMBL1413079 | 0.75 | NT5E (0.70) | NT5ENSD2CASP6DUSP3PTPN5 | |
| SCHEMBL1070221 | 0.75 | NT5E (0.70) | NT5ENSD2CASP6DUSP3PTPN5 | |
| SCHEMBL29429653 | 0.75 | NT5E (0.70) | NT5ENSD2CASP6DUSP3PTPN5 | |
| SCHEMBL25196311 | 0.74 | LCK (0.52) | NT5ENSD2CASP6DUSP3PTPN5 | |
| SCHEMBL30156858 | 0.74 | LCK (0.52) | NT5ENSD2CASP6DUSP3PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888406-B1 | AZO COMPOUNDS | AVECIA LTD (GB) | 2001-12-12 | — | — | EP | disclosed |