Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.63 |
| ▸ | NT5E | P21589 | 2/20 | 0.62 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.58 |
| ▸ | NSD2 | O96028 | 2/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26885948 | 0.95 | NT5E (0.68) | CASP6CTDSP1NT5EENPP2NSD2 | |
| SCHEMBL26885659 | 0.89 | CASP6 (0.60) | CASP6CTDSP1NT5EENPP2NSD2 | |
| SCHEMBL7814945 | 0.88 | CASP6 (0.68) | CASP6CTDSP1NT5EENPP2NSD2 | |
| SCHEMBL11211030 | 0.87 | PRMT1 (0.67) | CASP6CTDSP1NT5EENPP2NSD2 | |
| SCHEMBL10905567 | 0.87 | CASP6 (0.67) | CASP6CTDSP1NT5EENPP2NSD2 | |
| SCHEMBL6017879 | 0.86 | CASP6 (0.84) | CASP6CTDSP1NT5EENPP2NSD2 | |
| SCHEMBL11489790 | 0.86 | PRMT1 (0.66) | CASP6CTDSP1NT5EENPP2NSD2 | |
| SCHEMBL7897823 | 0.86 | CASP6 (0.65) | CASP6CTDSP1NT5EENPP2NSD2 | |
| SCHEMBL7795450 | 0.85 | NT5E (0.56) | CASP6CTDSP1NT5ENSD2DUSP3 | |
| SCHEMBL6568796 | 0.84 | CASP6 (0.78) | CASP6CTDSP1NT5EENPP2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381159-A1 | SMALL MOLECULE INHIBITORS OF CORONAVIRUS ATTACHMENT AND ENTRY, METHODS AND USES THEREOF | UNIVERSITY OF MIAMI | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381159-A1 | SMALL MOLECULE INHIBITORS OF CORONAVIRUS ATTACHMENT AND ENTRY, METHODS AND USES THEREOF | ACE2, ACE, SARS1 | CASP6 2657/4885CTDSP1 328/4885NT5E 1825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.