Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8532621 | 0.89 | ADRB2 (0.59) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL7840806 | 0.88 | ADRB2 (0.62) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL8531752 | 0.88 | ADRB2 (0.74) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL5397349 | 0.87 | ABCB11 (0.72) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL8530380 | 0.87 | ADRB2 (0.57) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL7791110 | 0.86 | ABCB11 (0.71) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL8527907 | 0.80 | ADRB2 (0.59) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL8088349 | 0.80 | ABCB11 (0.73) | ADRB2ADRB1ABCB11DRD2PDE4A | |
| SCHEMBL4535621 | 0.78 | ADRB2 (0.83) | ADRB2ADRB1ABCB11DRD2 | |
| SCHEMBL7837307 | 0.76 | ADRB2 (0.80) | ADRB2ADRB1ABCB11DRD2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918760-B1 | BIOLOGICALLY ACTIVE BENZOTHIAZOLONE ETHANAMINES | ASTRAZENECA AB (SE) | 2001-11-28 | — | — | EP | disclosed |