Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.49 |
| ▸ | MPEG1 | Q2M385 | 7/20 | 0.49 |
| ▸ | XIAP | P98170 | 2/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090989 | 0.90 | ALOX5 (0.49) | ALOX5MPEG1XIAPGPR84KDM4E | |
| SCHEMBL17123718 | 0.81 | ALOX5 (0.73) | ALOX5MPEG1XIAPGPR84KDM4E | |
| SCHEMBL17123726 | 0.79 | ALOX5 (0.73) | ALOX5MPEG1 | |
| SCHEMBL12387131 | 0.79 | ALOX5 (0.73) | ALOX5MPEG1 | |
| SCHEMBL11790353 | 0.71 | XIAP (0.41) | ALOX5XIAPKDM4EMEN1USP2 | |
| Hydrochloric Acid SCHEMBL28922225 | 0.71 | ACHE (0.57) | ALOX5MPEG1XIAPGPR84KDM4E | |
| SCHEMBL28655350 | 0.71 | ACHE (0.55) | ALOX5MPEG1XIAPGPR84KDM4E | |
| SCHEMBL28584301 | 0.70 | ALOX5 (0.50) | ALOX5MPEG1XIAPGPR84KDM4E | |
| SCHEMBL10701770 | 0.69 | STAT3 (0.85) | ALOX5MPEG1 | |
| SCHEMBL10702367 | 0.69 | STAT3 (0.85) | ALOX5MPEG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153028-A1 | AMINOSILANE ESTERS | Cognis Deutschland GmbH (DE) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000047588-A1 | AMINOSILANE ESTERS | COGNIS DEUTSCHLAND GMBH (DE) | 2000-08-17 | — | — | WO | disclosed |