Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795757 | 0.97 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL7792062 | 0.96 | SLC6A2 (0.41) | ALDH1A1CYP1A2CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL7794694 | 0.93 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL7792329 | 0.91 | SLC6A2 (0.40) | ALDH1A1CYP1A2CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL7795872 | 0.91 | SLC6A2 (0.42) | ALDH1A1CYP1A2CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL7792041 | 0.91 | SLC6A2 (0.47) | ALDH1A1SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL7794957 | 0.90 | MEN1 (0.46) | ALDH1A1SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL7786280 | 0.90 | SLC6A2 (0.39) | ALDH1A1CYP1A2CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL7795933 | 0.90 | SLC6A2 (0.41) | ALDH1A1CYP1A2CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL7786314 | 0.88 | SLC6A2 (0.36) | ALDH1A1CYP1A2CYP3A4SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |