Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795698 | 0.97 | ALDH1A1 (0.43) | ALDH1A1CYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL7794694 | 0.96 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL7792062 | 0.93 | SLC6A2 (0.41) | ALDH1A1CYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL7786314 | 0.91 | SLC6A2 (0.36) | ALDH1A1CYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL7795942 | 0.91 | SLC6A2 (0.38) | ALDH1A1CYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL7792122 | 0.91 | SLC6A2 (0.43) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7792225 | 0.90 | MEN1 (0.47) | ALDH1A1MEN1KMT2AELANEPDCD1LG2 | |
| SCHEMBL7786428 | 0.90 | CHRNB4 (0.36) | ALDH1A1CYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL7795746 | 0.90 | SLC6A2 (0.37) | ALDH1A1CYP1A2CYP3A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7792641 | 0.89 | CHRNB4 (0.35) | ALDH1A1CYP1A2CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |