Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370639 | 0.81 | CA1 (0.39) | TDP1ALDH1A1TSHRKDM4ECA2 | |
| SCHEMBL8974875 | 0.78 | TDP1 (0.42) | TDP1ATMALDH1A1TSHRKDM4E | |
| SCHEMBL18415682 | 0.76 | ALDH1A1 (0.45) | TDP1ATMALDH1A1TSHRKDM4E | |
| SCHEMBL27481998 | 0.75 | PTGDR2 (0.51) | TDP1ATMALDH1A1TSHRKDM4E | |
| SCHEMBL3027299 | 0.75 | GAA (0.43) | TDP1ATMALDH1A1KDM4EGAA | |
| SCHEMBL8582986 | 0.74 | TDP1 (0.40) | TDP1ATMALDH1A1TSHRKDM4E | |
| SCHEMBL28774590 | 0.74 | TDP1 (0.44) | TDP1ATMALDH1A1TSHRKDM4E | |
| SCHEMBL8582991 | 0.74 | TDP1 (0.40) | TDP1ATMALDH1A1TSHRKDM4E | |
| SCHEMBL12853863 | 0.74 | KMT2A (0.41) | ALDH1A1TSHRKDM4ERXRARXRB | |
| SCHEMBL12853879 | 0.74 | CA1 (0.56) | TDP1ALDH1A1TSHRKDM4ECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779886-B1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2001-12-05 | — | — | EP | disclosed |