Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140730 | 0.76 | PTGDR2 (0.62) | PTGDR2ALOX15USP2ALPLALDH1A1 | |
| SCHEMBL7795831 | 0.75 | TDP1 (0.42) | ALDH1A1TDP1TSHRLMNATP53 | |
| SCHEMBL29426974 | 0.74 | PTGDR2 (0.56) | PTGDR2ALOX15USP2ALPLALDH1A1 | |
| SCHEMBL1542948 | 0.74 | PTGDR2 (0.56) | PTGDR2ALOX15USP2ALPLALDH1A1 | |
| SCHEMBL4613709 | 0.73 | HSD17B10 (0.33) | PTGDR2ALOX15 | |
| SCHEMBL3982874 | 0.72 | PTGDR2 (0.62) | PTGDR2ALOX15USP2ALPLALDH1A1 | |
| SCHEMBL3982876 | 0.71 | PTGDR2 (0.65) | PTGDR2ALOX15USP2ALPLALDH1A1 | |
| SCHEMBL13748304 | 0.70 | PTGDR2 (0.64) | PTGDR2ALOX15USP2ALPLALDH1A1 | |
| SCHEMBL7587512 | 0.70 | PTGDR2 (0.51) | PTGDR2ALOX15USP2ALPLALDH1A1 | |
| SCHEMBL9860880 | 0.70 | PTGDR2 (0.51) | PTGDR2ALOX15USP2ALPLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1191243-C | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents | UNIV VANDERBILT (US) | 2005-03-02 | — | — | CN | disclosed |
| CN-1183126-C | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents | ���±ȶ��ش�ѧ | 2005-01-05 | — | — | CN | disclosed |
| CN-1157613-A | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents | PROCTER & GAMBLE (US) | 1997-08-20 | — | — | CN | disclosed |
| CN-1156993-A | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents | PROCTER & GAMBLE (US) | 1997-08-13 | — | — | CN | disclosed |