Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | FGB | P02675 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792699 | 0.98 | PDCD1LG2 (0.35) | PDCD1LG2CD274P2RY2P2RY4MEN1 | |
| SCHEMBL7796354 | 0.97 | SLC6A3 (0.37) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7795905 | 0.93 | TTR (0.36) | PDCD1LG2CD274P2RY2P2RY4MEN1 | |
| SCHEMBL7795920 | 0.91 | CHRNB4 (0.34) | PDCD1LG2CD274P2RY2P2RY4SLC6A2 | |
| SCHEMBL7796488 | 0.91 | TTR (0.36) | PDCD1LG2CD274P2RY2P2RY4MEN1 | |
| Hydrochloric Acid SCHEMBL7792171 | 0.90 | CHRNB4 (0.34) | PDCD1LG2CD274P2RY2P2RY4MEN1 | |
| SCHEMBL7795886 | 0.89 | TTR (0.37) | PDCD1LG2CD274P2RY2SLC6A2SLC6A4 | |
| SCHEMBL7796237 | 0.88 | HTR2A (0.36) | P2RY2 | |
| SCHEMBL7792460 | 0.87 | TTR (0.37) | PDCD1LG2CD274P2RY2SLC6A2SLC6A4 | |
| SCHEMBL7786168 | 0.87 | MEN1 (0.47) | PDCD1LG2CD274MEN1KMT2AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |