Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795897 | 0.89 | MEN1 (0.50) | MEN1KMT2APOLBCYP3A4HPGD | |
| SCHEMBL7932260 | 0.89 | MEN1 (0.53) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL8656540 | 0.86 | SMN1; SMN2 (0.54) | MEN1KMT2APOLBHPGDKDM4E | |
| SCHEMBL7794731 | 0.85 | SPHK2 (0.54) | POLBHPGDKDM4EALDH1A1RAB9A | |
| SCHEMBL7031470 | 0.85 | SPHK2 (0.54) | POLBHPGDKDM4EALDH1A1RAB9A | |
| SCHEMBL6608676 | 0.84 | KDM4E (0.55) | MEN1KMT2APOLBHPGDKDM4E | |
| SCHEMBL14093848 | 0.83 | TERT (0.40) | MEN1KMT2APOLBHPGDKDM4E | |
| SCHEMBL13865682 | 0.81 | FABP4 (0.49) | MEN1KMT2APOLBHPGDKDM4E | |
| SCHEMBL14160765 | 0.81 | EGFR (0.43) | MEN1KMT2APOLBHPGDKDM4E | |
| SCHEMBL22424935 | 0.80 | GAA (0.56) | MEN1KMT2AHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742210-B1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5962493-A | HYPOLIPEMIC AGENTS; ANTICHOLESTEROL AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0742210-A1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |