Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.30 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ioversol SCHEMBL24711 | 0.94 | LMNA (0.64) | LMNACYP2C19HIF1AEGFRSRC | |
| Ioversol SCHEMBL9745016 | 0.94 | LMNA (0.64) | LMNACYP2C19HIF1AEGFRSRC | |
| Ioversol SCHEMBL7794872 | 0.92 | LMNA (0.65) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9736495 | 0.92 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9196493 | 0.91 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL7795950 | 0.90 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9316965 | 0.90 | CYP2C19 (0.72) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL22661224 | 0.89 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9234595 | 0.89 | LMNA (0.61) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9317727 | 0.88 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558484-A1 | NOVEL X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1993-09-08 | — | — | EP | claimed |
| WO-1992009562-A1 | NOVEL X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1992-06-11 | — | — | WO | claimed |
| US-5019371-A | Novel x-ray contrast agents, compositions and methods | MALLINCKRODT MEDICAL, INC. (US) | 1991-05-28 | — | — | US | claimed |
| US-5356613-A | X-ray contrast agents, compositions and methods | MALLINCKRODT MEDICAL, INC. (US) | 1994-10-18 | — | — | US | disclosed |
| US-5356613-A | X-ray contrast agents, compositions and methods | MALLINCKRODT MEDICAL, INC. (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0558484-A1 | NOVEL X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1993-09-08 | — | — | EP | disclosed |
| EP-0558484-A1 | NOVEL X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992009562-A1 | NOVEL X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1992-06-11 | — | — | WO | disclosed |
| WO-1992009562-A1 | NOVEL X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1992-06-11 | — | — | WO | disclosed |
| US-5019371-A | Novel x-ray contrast agents, compositions and methods | MALLINCKRODT MEDICAL, INC. (US) | 1991-05-28 | — | — | US | disclosed |
| US-5019371-A | Novel x-ray contrast agents, compositions and methods | MALLINCKRODT MEDICAL, INC. (US) | 1991-05-28 | — | — | US | disclosed |