Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | SI | P14410 | 3/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794735 | 0.89 | KDM4E (0.37) | ALDH1A1NPSR1PTPN1KDM4EHRH3 | |
| SCHEMBL8594056 | 0.88 | SHMT2 (0.37) | SHMT2ALDH1A1NPSR1KDM4EMGAM | |
| SCHEMBL7794802 | 0.74 | ALDH1A1 (0.43) | ALDH1A1NPSR1PTPN1KDM4EMGAM | |
| SCHEMBL6701333 | 0.71 | PTPN1 (0.45) | ALDH1A1PTPN1KDM4EGAA | |
| SCHEMBL7786572 | 0.71 | ALDH1A1 (0.41) | ALDH1A1PTPN1KDM4EMGAMGAA | |
| SCHEMBL7571712 | 0.71 | PTPN1 (0.44) | ALDH1A1PTPN1KDM4EGAA | |
| SCHEMBL7792243 | 0.70 | KDM4E (0.47) | ALDH1A1NPSR1KDM4EHRH3 | |
| SCHEMBL7105642 | 0.68 | KDM4E (0.47) | ALDH1A1KDM4EHRH3 | |
| Iodide SCHEMBL7792207 | 0.68 | CYP1A1 (0.36) | ALDH1A1NPSR1KDM4EPDE10A | |
| Iodide SCHEMBL7786337 | 0.68 | CA1 (0.33) | ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |