SCHEMBL7796155

SCHEMBL7796155

CC(C)(C)CC(C)(C)c1cc(C(=O)O)cc(C(C)(C)C)c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.49
RECQL P46063 1/20 0.49
GLRA3 O75311 1/20 0.49
GLRB P48167 1/20 0.49
PTGS2 P35354 3/20 0.47
ALOX5 P09917 2/20 0.47
PTGS1 P23219 2/20 0.47
TNFRSF1A P19438 1/20 0.43
CA2 P00918 2/20 0.42
CA1 P00915 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
ALDH1A1 P00352 3/20 0.41
POLB P06746 2/20 0.41
TYR P14679 1/20 0.41
GAA P10253 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
GABBR2 O75899 1/20 0.41
GABBR1 Q9UBS5 1/20 0.41
RARA P10276 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11366614 0.95 CA12 (0.42) LMNARECQLGLRA3GLRBPTGS2
SCHEMBL15524547 0.87 CA12 (0.52) LMNAGLRA3GLRBPTGS2CA2
SCHEMBL227202 0.86 GLRA3 (0.63) LMNARECQLGLRA3GLRBPTGS2
SCHEMBL3809011 0.85 MEN1 (0.38) LMNAGLRA3GLRBCA2CA1
SCHEMBL7792941 0.85 LMNA (0.54) LMNARECQLGLRA3GLRBPTGS2
SCHEMBL3809056 0.84 ALDH1A1 (0.42) LMNARECQLGLRA3GLRBPTGS2
SCHEMBL9355788 0.84 GLRA3 (0.61) LMNARECQLGLRA3GLRBPTGS2
SCHEMBL8659247 0.84 GLRA3 (0.61) LMNARECQLGLRA3GLRBPTGS2
Hydrochloric Acid SCHEMBL1943524 0.84 GLRA3 (0.61) LMNARECQLGLRA3GLRBPTGS2
SCHEMBL7629603 0.84 GLRA3 (0.61) LMNARECQLGLRA3GLRBPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed