SCHEMBL7796414

SCHEMBL7796414

C=C(CC(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)Cl)C(=O)OCC

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
TSHR P16473 1/20 0.41
ALOX15 P16050 1/20 0.36
GLO1 Q04760 1/20 0.34
MAPT P10636 1/20 0.32
CYP2D6 P10635 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7794980 0.77 ALDH1A1 (0.44) ALDH1A1TSHRALOX15GLO1MAPT
SCHEMBL12130916 0.72 ALDH1A1 (0.45) ALDH1A1TSHRALOX15GLO1MAPT
SCHEMBL9546127 0.71 ALDH1A1 (0.44) ALDH1A1TSHRALOX15GLO1MAPT
SCHEMBL9745910 0.70 ALDH1A1 (0.52) ALDH1A1TSHRALOX15GLO1MAPT
SCHEMBL9746477 0.70 ALDH1A1 (0.52) ALDH1A1TSHRALOX15GLO1MAPT
SCHEMBL323091 0.69
SCHEMBL2770601 0.69 MEN1 (0.43) ALDH1A1TSHRALOX15GLO1MAPT
SCHEMBL14086409 0.69 ALDH1A1 (0.39) ALDH1A1TSHRALOX15GLO1MAPT
SCHEMBL17687582 0.68 ALDH1A1 (0.41) ALDH1A1TSHRALOX15GLO1MAPT
SCHEMBL22490385 0.68 ALDH1A1 (0.41) ALDH1A1TSHRGLO1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0540353-B1 Liquid crystal display SHARP KK (JP) 2001-12-12 EP disclosed
US-5394256-A Encapsulated liquid crystal in liquid crystal material where one liquid crystal has positive birefringence and dielectric anisotropy, the other has only one positive of birefringence and dielectric anisotropy SHARP KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
EP-0540353-A2 Liquid crystal display SHARP KABUSHIKI KAISHA (JP) 1993-05-05 EP disclosed