SCHEMBL7794980

SCHEMBL7794980

C=C(C(=O)OCC)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
TSHR P16473 1/20 0.44
GLO1 Q04760 1/20 0.37
CASP1 P29466 1/20 0.36
ALOX15 P16050 1/20 0.35
MAPT P10636 3/20 0.34
NPSR1 Q6W5P4 1/20 0.33
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP2C9 P11712 1/20 0.32
THRB P10828 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SOAT1 P35610 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9746477 0.78 ALDH1A1 (0.52) ALDH1A1TSHRGLO1CASP1ALOX15
SCHEMBL9745910 0.78 ALDH1A1 (0.52) ALDH1A1TSHRGLO1CASP1ALOX15
SCHEMBL7796414 0.77 ALDH1A1 (0.41) ALDH1A1TSHRGLO1CASP1ALOX15
SCHEMBL9746840 0.77 ALDH1A1 (0.47) ALDH1A1TSHRGLO1CASP1ALOX15
SCHEMBL11477409 0.71 ALDH1A1 (0.48) ALDH1A1TSHRGLO1CASP1ALOX15
SCHEMBL1896769 0.71 ALDH1A1 (0.48) ALDH1A1TSHRGLO1CASP1ALOX15
SCHEMBL9745097 0.70 ALDH1A1 (0.47) ALDH1A1TSHRGLO1CASP1ALOX15
SCHEMBL9746132 0.70 ALDH1A1 (0.47) ALDH1A1TSHRGLO1CASP1ALOX15
SCHEMBL304056 0.70 ALDH1A1 (0.47) ALDH1A1TSHRGLO1ALOX15MAPT
SCHEMBL8744223 0.70 ALDH1A1 (0.47) ALDH1A1TSHRGLO1ALOX15MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0540353-B1 Liquid crystal display SHARP KK (JP) 2001-12-12 EP disclosed
US-5394256-A Encapsulated liquid crystal in liquid crystal material where one liquid crystal has positive birefringence and dielectric anisotropy, the other has only one positive of birefringence and dielectric anisotropy SHARP KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
EP-0540353-A2 Liquid crystal display SHARP KABUSHIKI KAISHA (JP) 1993-05-05 EP disclosed