Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792344 | 0.99 | PTGDR2 (0.43) | CYP1A2CYP2C9CYP2C19PTGDR2MAPT | |
| SCHEMBL7792081 | 0.99 | PTGDR2 (0.43) | CYP1A2CYP2C9CYP2C19PTGDR2MAPT | |
| SCHEMBL7796343 | 0.99 | PTGDR2 (0.43) | CYP1A2CYP2C9CYP2C19PTGDR2MAPT | |
| SCHEMBL7794693 | 0.87 | PTGDR2 (0.47) | PTGDR2ALDH1A1RECQLSMN1; SMN2ASAH1 | |
| SCHEMBL7794772 | 0.85 | CYP1A2 (0.45) | CYP1A2PTGDR2ALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL7795675 | 0.84 | GAA (0.54) | PTGDR2MAPTALDH1A1GAAPSMD14 | |
| SCHEMBL7792121 | 0.84 | IDO1 (0.47) | PTGDR2SMN1; SMN2L3MBTL1ASAH1KDM4E | |
| SCHEMBL8402493 | 0.82 | ALDH1A1 (0.56) | PTGDR2MAPTALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL8400685 | 0.81 | P2RX3 (0.34) | MAPTALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL7792456 | 0.81 | BACE1 (0.39) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742210-B1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-5962493-A | HYPOLIPEMIC AGENTS; ANTICHOLESTEROL AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| EP-0742210-A1 | 2-MERCAPTOBENZIMIDAZOLE DERIVATIVE AND ANTIHYPERLIPEMIC OR ANTIARTERIOSCLEROTIC AGENT CONTAINING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |