Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 3/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794771 | 1.00 | TTR (0.42) | TTRKCNA3FLT3P2RY2ALDH1A1 | |
| SCHEMBL7794675 | 0.94 | TTR (0.42) | TTRKCNA3P2RY2ALDH1A1KDM4E | |
| SCHEMBL7786304 | 0.94 | TTR (0.42) | TTRKCNA3P2RY2ALDH1A1KDM4E | |
| SCHEMBL7795946 | 0.94 | CYP1A2 (0.41) | KCNA3FLT3ALDH1A1KDM4ETDP1 | |
| SCHEMBL7791883 | 0.94 | CYP1A2 (0.41) | KCNA3FLT3ALDH1A1KDM4ETDP1 | |
| SCHEMBL7796600 | 0.94 | CYP1A2 (0.40) | KCNA3FLT3ALDH1A1 | |
| SCHEMBL7792181 | 0.93 | CYP1A2 (0.41) | TTRKCNA3P2RY2MAOB | |
| SCHEMBL7786318 | 0.92 | CYP1A2 (0.42) | TTRP2RY2ALDH1A1KDM4EMAOB | |
| SCHEMBL7796590 | 0.92 | CYP1A2 (0.42) | TTRP2RY2ALDH1A1KDM4EMAOB | |
| SCHEMBL7792112 | 0.91 | ALDH1A1 (0.46) | KCNA3FLT3ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |