SCHEMBL7796475

SCHEMBL7796475

CCC(C)(C)c1cc(C(=O)O)cc(C(C)(C)C)c1OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNFRSF1A P19438 2/20 0.48
TPMT P51580 5/20 0.44
RARG P13631 3/20 0.41
RXRA P19793 1/20 0.41
PPARG P37231 1/20 0.41
RARA P10276 2/20 0.40
RARB P10826 2/20 0.40
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
CYP2C9 P11712 1/20 0.39
RAB9A P51151 1/20 0.39
EPHX2 P34913 1/20 0.39
NR1H4 Q96RI1 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA3 P07451 1/20 0.39
PKM P14618 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3637333 0.88 TNFRSF1A (0.56) TNFRSF1ATPMTRARGRARARARB
SCHEMBL7786607 0.86 TNFRSF1A (0.47) TNFRSF1ATPMTRARGRARARARB
SCHEMBL7792201 0.86 TPMT (0.43) TNFRSF1ATPMTRARGRXRAPPARG
SCHEMBL7792498 0.86 TPMT (0.43) TNFRSF1ATPMTRARGRXRAPPARG
SCHEMBL7786612 0.84 TNFRSF1A (0.46) TNFRSF1ATPMTRARGRARARARB
SCHEMBL7792476 0.83 TNFRSF1A (0.46) TNFRSF1ATPMTRARGRARARARB
SCHEMBL7796152 0.82 NR1H4 (0.43) TNFRSF1ARARGRXRAPPARGNR1H4
SCHEMBL7943237 0.80 TNFRSF1A (0.40) TNFRSF1ARARGRXRAPPARGPOLB
SCHEMBL7792487 0.80 GAA (0.40) TNFRSF1ARARGRXRAPPARGKCNH2
SCHEMBL7792403 0.79 TNFRSF1A (0.48) TNFRSF1ATPMTRARGRARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed