SCHEMBL7792201

SCHEMBL7792201

CCC(C)(C)c1cc(C(=O)O)cc(C)c1OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 6/20 0.43
RARG P13631 2/20 0.40
RXRA P19793 1/20 0.40
PPARG P37231 1/20 0.40
ALDH1A1 P00352 1/20 0.39
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
CYP2C9 P11712 1/20 0.38
RAB9A P51151 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA3 P07451 1/20 0.38
PKM P14618 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792416 0.87 TPMT (0.40) TPMTRARGALDH1A1POLBCA12
SCHEMBL7796475 0.86 TNFRSF1A (0.48) TPMTRARGRXRAPPARGNPC1
SCHEMBL7792498 0.85 TPMT (0.43) TPMTRARGRXRAPPARGALDH1A1
SCHEMBL7792421 0.85 PLA2G2A (0.40) TPMTCNR2TSHRRARB
SCHEMBL7792403 0.84 TNFRSF1A (0.48) TPMTRARGALDH1A1CA12CA1
SCHEMBL7942531 0.81 ESR1 (0.42) RARGRXRAPPARGALDH1A1CYP2C9
SCHEMBL3814374 0.80 ESR1 (0.39) TPMTALDH1A1NPC1POLBCYP2C9
SCHEMBL7796602 0.79 THRB (0.40) RARGRXRAPPARGALDH1A1TSHR
SCHEMBL312132 0.78 TPMT (0.55) TPMTALDH1A1CA12CA1CA2
SCHEMBL7792867 0.77 FFAR4 (0.41) RARGRXRAPPARGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed