SCHEMBL7792487

SCHEMBL7792487

CCC(C)(C)c1cc(CCC(=O)O)cc(C(C)(C)C)c1OC

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.40
KMT2A Q03164 2/20 0.40
RXRA P19793 2/20 0.40
RXRB P28702 1/20 0.40
RXRG P48443 1/20 0.40
THRA P10827 5/20 0.39
THRB P10828 5/20 0.39
FFAR1 O14842 2/20 0.39
TNFRSF1A P19438 1/20 0.39
RARG P13631 1/20 0.38
PPARG P37231 1/20 0.38
VCAM1 P19320 2/20 0.37
KCNH2 Q12809 1/20 0.36
LMNA P02545 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7796603 0.91 GAA (0.45) GAAKMT2ARXRARXRBRXRG
SCHEMBL7796410 0.88 THRA (0.39) KMT2ARXRARXRBRXRGTHRA
SCHEMBL7792867 0.88 FFAR4 (0.41) KMT2ARXRATHRATHRBFFAR1
SCHEMBL7796625 0.88 GAA (0.39) GAAKMT2ARXRARXRBRXRG
SCHEMBL7796629 0.86 THRA (0.46) GAAKMT2ARXRARXRBRXRG
SCHEMBL7796152 0.86 NR1H4 (0.43) GAARXRARXRBRXRGTHRA
SCHEMBL7792806 0.84 GAA (0.41) GAAKMT2ARXRARXRBRXRG
SCHEMBL7792155 0.83 FFAR1 (0.44) GAAKMT2ARXRARXRBRXRG
SCHEMBL6567472 0.82 DHFR (0.38) GAAKMT2ARXRATNFRSF1ARARG
SCHEMBL7940250 0.82 ALOX5 (0.39) GAAKMT2AVCAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed