Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 16/20 | 0.87 |
| ▸ | THRB | P10828 | 1/20 | 0.82 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | FYN | P06241 | 2/20 | 0.58 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propiconazole SCHEMBL3005219 | 0.93 | CYP3A4 (1.00) | CYP3A4THRBHSP90AA1LMNAFYN | |
| Propiconazole SCHEMBL9321555 | 0.93 | CYP3A4 (1.00) | CYP3A4THRBHSP90AA1LMNAFYN | |
| Propiconazole SCHEMBL21081 | 0.93 | CYP3A4 (1.00) | CYP3A4THRBHSP90AA1LMNAFYN | |
| Propiconazole SCHEMBL30149161 | 0.93 | CYP3A4 (1.00) | CYP3A4THRBHSP90AA1LMNAFYN | |
| Propiconazole SCHEMBL2522027 | 0.93 | CYP3A4 (1.00) | CYP3A4THRBHSP90AA1LMNAFYN | |
| Propiconazole SCHEMBL5598958 | 0.93 | CYP3A4 (1.00) | CYP3A4THRBHSP90AA1LMNAFYN | |
| Propiconazole SCHEMBL29795708 | 0.93 | CYP3A4 (1.00) | CYP3A4THRBHSP90AA1LMNAFYN | |
| Propiconazole SCHEMBL30182039 | 0.93 | CYP3A4 (1.00) | CYP3A4THRBHSP90AA1LMNAFYN | |
| Propiconazole SCHEMBL29404305 | 0.93 | CYP3A4 (1.00) | CYP3A4THRBHSP90AA1LMNAFYN | |
| Nitric Acid SCHEMBL11541298 | 0.93 | CYP3A4 (0.76) | CYP3A4THRBHSP90AA1LMNAFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010047015-A1 | Pharmaceutical composition for inhibiting the growth of cancers | CAMDEN JAMES BERGER (US) | 2001-11-29 | — | — | US | claimed |
| US-20010039291-A1 | Compositions and methods of treatment for cancer or viral infections | THE PROCTER & GAMBLE COMPANY | 2001-11-08 | — | — | US | claimed |
| US-6228876-B1 | ADMINISTERING 1-(1,3-DIOXOLAN-2-YLMETHY)L- OR 1-(1,3-DIOXAN-2-YLMETHYL)-1H-1,2,4-TRIAZOLE DERIVATIVE | THE PROCTER & GAMBLE COMPANY | 2001-05-08 | — | — | US | claimed |
| US-6200992-B1 | ADMINISTERING 1H-1,2,4-TRIAZOLE DERIVATIVE, CHEMOTHERAPEUTIC AGENT, AND POTENTIATOR; ANTICARCINOGENIC, ANTITUMOR AGENTS | THE PROCTER & GAMBLE COMPANY | 2001-03-13 | — | — | US | claimed |
| US-6110953-A | Pharmaceutical composition for inhibiting the growth of cancers | THE PROCTER & GAMBLE COMPANY (US) | 2000-08-29 | — | — | US | claimed |
| US-6025377-A | 1H-1,2,4-TRIAZOLE DERIVATIVE. THESE COMPOUNDS CAN ALSO BE USED TO TREAT VIRAL INFECTIONS. | THE PROCTER & GAMBLE COMPANY (US) | 2000-02-15 | — | — | US | claimed |
| US-5872142-A | 1,3-DIOXANE OR -DIOXOLANE DERIVATIVES OF 1H-1,2,4-TRIAZOLE | THE PROCTER & GAMBLE COMPANY (US) | 1999-02-16 | — | — | US | claimed |
| US-5770616-A | 1,2,4-TRIAZOLE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-23 | — | — | US | claimed |
| EP-0841920-A2 | USE OF 1H-1,2,4-TRIAZOLE DERIVATIVES FOR INHIBITING THE GROWTH OF CANCERS | THE PROCTER & GAMBLE COMPANY (US) | 1998-05-20 | — | — | EP | claimed |
| EP-0831814-A1 | USE OF 1,2,4-TRIAZOLE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF CANCERS | THE PROCTER & GAMBLE COMPANY (US) | 1998-04-01 | — | — | EP | claimed |
| WO-1997005872-A2 | USE OF 1H-1,2,4-TRIAZOLE DERIVATIVES FOR INHIBITING THE GROWTH OF CANCERS | THE PROCTER & GAMBLE COMPANY (US) | 1997-02-20 | — | — | WO | claimed |
| WO-1996040119-A1 | USE OF 1,2,4-TRIAZOLE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF CANCERS | THE PROCTER & GAMBLE COMPANY (US) | 1996-12-19 | — | — | WO | claimed |
| EP-0252875-B1 | MICROBICIDAL AGENT | CIBA-GEIGY AG (CH) | 1993-01-27 | — | — | EP | claimed |
| EP-0252875-A2 | Microbicidal agent | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | claimed |
| US-4160838-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-07-10 | — | — | US | claimed |
| US-4079062-A | ANTIMICROBIAL, PLANT GROWTH REGULATORS; 1-(B-ARYL)ETHYL-1H-1,2,4-TRIAZOLE KETALS | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-03-14 | — | — | US | claimed |
| US-20010047015-A1 | Pharmaceutical composition for inhibiting the growth of cancers | CAMDEN JAMES BERGER (US) | 2001-11-29 | — | — | US | disclosed |
| US-20010039291-A1 | Compositions and methods of treatment for cancer or viral infections | THE PROCTER & GAMBLE COMPANY | 2001-11-08 | — | — | US | disclosed |
| US-5026719-A | Synergistic combination of triazole fungicide and morpholine alkylarylsulfonate | CIBA-GEIGY CORPORATION (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0252875-A2 | Microbicidal agent | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010047015-A1 | Pharmaceutical composition for inhibiting the growth of cancers | MKI67, CCNI, MYC | CYP3A4 152/4885THRB 1259/4885HSP90AA1 1800/4885 |
| US-20010039291-A1 | Compositions and methods of treatment for cancer or viral infections | TP53, HAVCR2, MAVS | CYP3A4 1564/4885THRB 1657/4885HSP90AA1 631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.