SCHEMBL7797183

SCHEMBL7797183

Cc1cc(C2=CC(=O)NC2=O)ccc1C1=CC(=O)NC1=O

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.35
CLK4 Q9HAZ1 2/20 0.35
DAPK3 O43293 1/20 0.35
NTRK1 P04629 1/20 0.35
PIM1 P11309 1/20 0.35
FLT3 P36888 1/20 0.35
ROCK1 Q13464 1/20 0.35
PDE3B Q13370 13/20 0.34
PDE3A Q14432 13/20 0.34
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31
CDC7 O00311 1/20 0.30
ROCK2 O75116 1/20 0.30
MAP4K4 O95819 1/20 0.30
CDK2 P24941 1/20 0.30
MKNK2 Q9HBH9 1/20 0.30
IRAK4 Q9NWZ3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29395435 0.95 GSK3B (0.39) GSK3BCLK4DAPK3NTRK1PIM1
SCHEMBL15741723 0.95 GSK3B (0.39) GSK3BCLK4DAPK3NTRK1PIM1
SCHEMBL29363128 0.86 ACACB (0.38) MAOAMAOB
SCHEMBL548315 0.86 ACACB (0.38) MAOAMAOB
SCHEMBL27726534 0.86 NOTUM (0.40) MAPT
SCHEMBL2479846 0.84 GAA (0.46) PDE3BPDE3AGAAMAPTMAOA
SCHEMBL21495981 0.81 HSD17B1 (0.41) GSK3BPIM1MAPTCDC7
SCHEMBL29395839 0.80 TGM2 (0.40) MAPT
SCHEMBL29564109 0.80 ACACB (0.35)
SCHEMBL29576432 0.80 PDE3B (0.33) PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117881759-A Thermoplastic resin composition, resin sheet, and laminate 宝理塑料赢创有限公司 2024-04-12 CN disclosed
US-20010018105-A1 Polyolefin molding material DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) 2001-08-30 US disclosed
EP-1118807-A2 Multilayered plastic pipe with good layer adhesion Degussa AG (DE) 2001-07-25 EP disclosed
EP-1041103-A2 Polyester and elastomer composite article Degussa-Hüls Aktiengesellschaft (DE) 2000-10-04 EP disclosed
EP-1041104-A2 Polyester and siliconrubber composite article Degussa-Hüls Aktiengesellschaft (DE) 2000-10-04 EP disclosed
EP-0683195-B1 Process for preparing composite articles from polyesters and rubbers HUELS CHEMISCHE WERKE AG (DE) 1998-04-08 EP disclosed
US-5552460-A HARD POLYESTER, VULCANIZING SOFT RUBBER, A BISMALEIMIDE HUELS AKTIENGESELLSCHAFT (DE) 1996-09-03 US disclosed
EP-0683195-A2 Process for preparing composite articles from polyesters and rubbers HÜLS AKTIENGESELLSCHAFT (DE) 1995-11-22 EP disclosed