Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797394 | 0.89 | TSHR (0.50) | TSHRSMN1; SMN2RAB9APKMHSD17B10 | |
| SCHEMBL7791065 | 0.84 | TSHR (0.47) | TSHRSMN1; SMN2RAB9APKMHSD17B10 | |
| SCHEMBL7800500 | 0.82 | NPSR1 (0.47) | TSHRPKMPRKCAALDH1A1 | |
| SCHEMBL7797340 | 0.78 | SMN1; SMN2 (0.54) | TSHRSMN1; SMN2PKMHSD17B10ALDH1A1 | |
| SCHEMBL17530080 | 0.77 | PRKCA (0.43) | TSHRSMN1; SMN2PRKCA | |
| SCHEMBL18315205 | 0.76 | ALDH1A1 (0.47) | TSHRSMN1; SMN2RAB9APRKCAALDH1A1 | |
| SCHEMBL7797307 | 0.75 | SMN1; SMN2 (0.51) | TSHRSMN1; SMN2PKMHSD17B10ALDH1A1 | |
| SCHEMBL16803291 | 0.75 | TSHR (0.67) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL160208 | 0.75 | TSHR (0.73) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL17530065 | 0.75 | TSHR (0.40) | TSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1164125-A1 | ADAMANTANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Daicel Chemical Industries, Ltd. (JP) | 2001-12-19 | — | — | EP | disclosed |