Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799315 | 0.81 | NPSR1 (0.55) | NPSR1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL7801830 | 0.81 | SMN1; SMN2 (0.41) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7797408 | 0.79 | NPSR1 (0.46) | NPSR1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL7797337 | 0.77 | NPSR1 (0.47) | NPSR1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL21636809 | 0.76 | GSTP1 (0.38) | ALDH1A1LMNAATMSMN1; SMN2 | |
| SCHEMBL7125107 | 0.76 | ALDH1A1 (0.32) | ALDH1A1LMNATHRBHTTSMN1; SMN2 | |
| SCHEMBL20673387 | 0.71 | PRKCA (0.49) | NPSR1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL18232669 | 0.71 | NPSR1 (0.48) | NPSR1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL18232665 | 0.71 | ALDH1A1 (0.56) | NPSR1L3MBTL1ALDH1A1LMNAABL1 | |
| SCHEMBL691923 | 0.70 | NPSR1 (0.61) | NPSR1MEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1164125-A1 | ADAMANTANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Daicel Chemical Industries, Ltd. (JP) | 2001-12-19 | — | — | EP | disclosed |