Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7506626 | 0.85 | PTPN1 (0.81) | PTPN1HSP90AA1 | |
| SCHEMBL7801710 | 0.84 | PTPN1 (1.00) | PTPN1HSP90AA1 | |
| SCHEMBL7503022 | 0.82 | PTPN1 (0.80) | PTPN1 | |
| SCHEMBL7504516 | 0.81 | PTPN1 (0.65) | PTPN1 | |
| SCHEMBL6069407 | 0.80 | PTPN1 (0.91) | PTPN1 | |
| SCHEMBL7498091 | 0.80 | PTPN1 (0.68) | PTPN1HSP90AA1 | |
| SCHEMBL7496678 | 0.80 | PTPN1 (1.00) | PTPN1 | |
| SCHEMBL7496706 | 0.74 | PTPN1 (0.67) | PTPN1 | |
| SCHEMBL7686456 | 0.74 | PTPN1 (0.71) | PTPN1 | |
| SCHEMBL7497935 | 0.73 | PTPN1 (0.63) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010053785-A1 | Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia | WYETH | 2001-12-20 | — | — | US | disclosed |
| US-20010041715-A1 | Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia | AMERICAN HOME PRODUCTS | 2001-11-15 | — | — | US | disclosed |
| EP-1077967-A2 | BIPHENYL OXO-ACETIC ACIDS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058518-A2 | BIPHENYL OXO-ACETIC ACIDS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010053785-A1 | Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia | GPR119, INSR, IAPP | PTPN1 1004/4885HSP90AA1 4122/4885 |
| US-20010041715-A1 | Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia | GPR119, INSR, IAPP | PTPN1 1004/4885HSP90AA1 4122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.