Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31171150 | 0.86 | PTPN22 (0.58) | PTPN22CYP1A2NSD2OPRM1OPRD1 | |
| SCHEMBL7796050 | 0.86 | PTPN22 (0.58) | PTPN22CYP1A2NSD2OPRM1OPRD1 | |
| SCHEMBL31171149 | 0.80 | ALDH1A1 (0.62) | CYP1A2HSD17B10ALDH1A1KDM4ETHRB | |
| SCHEMBL25412675 | 0.80 | ALDH1A1 (0.62) | CYP1A2HSD17B10ALDH1A1KDM4ETHRB | |
| SCHEMBL214870 | 0.79 | NSD2 (0.54) | PTPN22CYP1A2NSD2OPRM1OPRD1 | |
| SCHEMBL29360295 | 0.79 | NSD2 (0.54) | PTPN22CYP1A2NSD2OPRM1OPRD1 | |
| SCHEMBL5894727 | 0.79 | HSD17B10 (0.56) | PTPN22CYP1A2NSD2OPRM1OPRD1 | |
| SCHEMBL30772437 | 0.78 | CYP1A2 (0.56) | PTPN22CYP1A2NSD2OPRM1OPRD1 | |
| SCHEMBL24266684 | 0.78 | ALDH1A1 (0.45) | PTPN22CYP1A2NSD2OPRM1OPRD1 | |
| SCHEMBL2835702 | 0.78 | HSD17B10 (0.67) | CYP1A2HSD17B10ALDH1A1KDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731105-B1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL CO (JP) | 2001-12-05 | — | — | EP | disclosed |
| US-5621129-A | Optically active tertiary phosphine compound, transition metal complex comprising the same as ligand and process for preparing optically active organic silicon compound using said transition metal complex | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0731105-A1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-09-11 | — | — | EP | disclosed |