Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 14/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.32 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787713 | 0.80 | CYP11B1 (0.37) | SIRT2ENPP2CYP11B1CYP11B2 | |
| SCHEMBL15487989 | 0.77 | CYP11B1 (0.40) | SIRT2ENPP2CYP11B1CYP11B2 | |
| SCHEMBL7787709 | 0.77 | CYP11B1 (0.37) | SIRT2ENPP2CYP11B1CYP11B2 | |
| SCHEMBL7784539 | 0.75 | CYP11B1 (0.40) | SIRT2ENPP2CYP11B1CYP11B2 | |
| SCHEMBL7786406 | 0.75 | CYP11B1 (0.40) | SIRT2ENPP2CYP11B1CYP11B2 | |
| SCHEMBL7786397 | 0.73 | CYP11B1 (0.39) | SIRT2ENPP2CYP11B1CYP11B2 | |
| SCHEMBL8608329 | 0.73 | CYP11B1 (0.39) | SIRT2ENPP2CYP11B1CYP11B2 | |
| SCHEMBL26643915 | 0.73 | SIRT2 (0.35) | SIRT2ENPP2CYP11B1CYP11B2 | |
| SCHEMBL7787692 | 0.72 | SIRT2 (0.41) | SIRT2ENPP2CYP11B1CYP11B2 | |
| SCHEMBL855359 | 0.71 | GAA (0.38) | SIRT2ENPP2CYP11B1CYP11B2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010047100-A1 | Chiral imidazoyl intermediates for the synthesis of 2-(4-imidazoyl)-cyclopropyl derivatives | KJAERSGAARD HANS JOERGEN (DK) | 2001-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010047100-A1 | Chiral imidazoyl intermediates for the synthesis of 2-(4-imidazoyl)-cyclopropyl derivatives | HRH4, HRH2, HRH1 | SIRT2 2591/4885ENPP2 920/4885CYP11B1 3958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.