Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 14/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787692 | 0.83 | SIRT2 (0.41) | CYP11B1CYP11B2ENPP2SIRT2 | |
| SCHEMBL7784539 | 0.80 | CYP11B1 (0.40) | CYP11B1CYP11B2ENPP2SIRT2MEN1 | |
| SCHEMBL7786406 | 0.80 | CYP11B1 (0.40) | CYP11B1CYP11B2ENPP2SIRT2MEN1 | |
| SCHEMBL15487989 | 0.80 | CYP11B1 (0.40) | CYP11B1CYP11B2ENPP2SIRT2KCNA3 | |
| SCHEMBL7787713 | 0.79 | CYP11B1 (0.37) | CYP11B1CYP11B2ENPP2SIRT2 | |
| SCHEMBL7786397 | 0.79 | CYP11B1 (0.39) | CYP11B1CYP11B2ENPP2SIRT2MEN1 | |
| SCHEMBL7787709 | 0.77 | CYP11B1 (0.37) | CYP11B1CYP11B2ENPP2SIRT2 | |
| Formic Acid SCHEMBL7797545 | 0.73 | SIRT2 (0.37) | CYP11B1CYP11B2ENPP2SIRT2 | |
| SCHEMBL31646062 | 0.72 | ENPP2 (0.34) | CYP11B1CYP11B2ENPP2SIRT2 | |
| SCHEMBL1375313 | 0.72 | HSD11B1 (0.36) | CYP11B1CYP11B2ENPP2SIRT2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990317-A | HISTAMINE H3 RECEPTOR ANTAGONIST FOR TREATING CNS DISORDERS INVOLVING ATTENTION OR COGNITIVE DISORDERS | GLIATECH, INC. (US) | 1999-11-23 | — | — | US | disclosed |