Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17476699 | 0.73 | AKT2 (0.50) | AKT2CHEK1DYRK1AACVR1MAPK1 | |
| SCHEMBL17561029 | 0.72 | AKT2 (0.58) | AKT2CHEK1DYRK1AACVR1MAPK1 | |
| SCHEMBL16209719 | 0.67 | AKT2 (0.79) | AKT2CHEK1DYRK1AACVR1MAPK1 | |
| SCHEMBL16181370 | 0.67 | — | — | |
| SCHEMBL6434684 | 0.64 | CD44 (0.41) | ALDH1A1LMNAMAPTHSD17B10NPSR1 | |
| SCHEMBL11996675 | 0.64 | NPC1 (0.36) | SMN1; SMN2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL3279505 | 0.63 | MAP4K1 (0.40) | SMN1; SMN2 | |
| SCHEMBL15489054 | 0.63 | AOC3 (0.35) | NPSR1 | |
| SCHEMBL1230218 | 0.63 | METAP2 (0.44) | SMN1; SMN2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL21262737 | 0.63 | AKT2 (0.70) | AKT2CHEK1DYRK1AACVR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010027242-A1 | Low monomer content NCO prepolymers based on | DEGUSSA AG (DE) | 2001-10-04 | — | — | US | claimed |