Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | GLA | P06280 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | CASP1 | P29466 | 2/20 | 0.71 |
| ▸ | CASP7 | P55210 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6478947 | 0.85 | KDM4E (0.61) | KDM4EHSD17B10ALDH1A1GLAGAA | |
| SCHEMBL7798964 | 0.84 | KDM4E (0.74) | KDM4EHSD17B10ALDH1A1GLAGAA | |
| SCHEMBL8374891 | 0.84 | HSD17B3 (0.61) | KDM4EHSD17B10ALDH1A1GLAGAA | |
| SCHEMBL7023152 | 0.83 | KDM4E (1.00) | KDM4EHSD17B10ALDH1A1GLAGAA | |
| SCHEMBL26458893 | 0.80 | KDM4E (1.00) | KDM4EHSD17B10ALDH1A1GLAGAA | |
| SCHEMBL7576024 | 0.80 | KDM4E (0.74) | KDM4EHSD17B10ALDH1A1GLAGAA | |
| SCHEMBL27554307 | 0.80 | ALDH1A1 (0.49) | KDM4EHSD17B10ALDH1A1GLAGAA | |
| SCHEMBL9545054 | 0.78 | KDM4E (0.69) | KDM4EHSD17B10ALDH1A1GLAGAA | |
| SCHEMBL4706717 | 0.78 | KDM4E (0.64) | KDM4EHSD17B10ALDH1A1GLAGAA | |
| SCHEMBL14925305 | 0.77 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900230-B1 | ESCULETIN DERIVATIVES | IDG UK LTD (GB) | 2001-12-12 | — | — | EP | disclosed |
| US-6287798-B1 | COMPOUND WHICH IS HYDROLYZABLE BY MICROORGANISMS FOR DETECTION IN SAMPLES; FORMS BLACK, INSOLUBLE, NONDIFFUSABLE COMPOUND | IDG (UK) LIMITED (GB) | 2001-09-11 | — | — | US | disclosed |
| US-6008008-A | 6- OR 7-SUBSTITUTED DERIVATIVES WHICH ARE MICROBIALLY HYDROLYZABLE TO FLUORESCENT, IRON CHELATING MOIETIES WHICH ARE NONDIFFUSING IN AGAR AND OTHER AQUEOUS ENVIRONMENTS; FOR DETECTION OF MICROORGANISMS | IDG (UK) LIMITED (GB) | 1999-12-28 | — | — | US | disclosed |
| EP-0900230-A2 | ESCULETIN DERIVATIVES | IDG (UK) Limited (GB) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041138-A2 | ESCULETIN DERIVATIVES | IDG (UK) LIMITED (GB) | 1997-11-06 | — | — | WO | disclosed |