⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5183762 | 1.00 | — | — | |
| SCHEMBL7756625 | 0.78 | — | — | |
| SCHEMBL7755113 | 0.78 | — | — | |
| Ethylene Glycol SCHEMBL7888599 | 0.75 | ALDH1A1 (0.38) | — | |
| SCHEMBL892356 | 0.75 | — | — | |
| SCHEMBL2995044 | 0.75 | — | — | |
| SCHEMBL892357 | 0.75 | — | — | |
| SCHEMBL4936077 | 0.74 | — | — | |
| SCHEMBL4632139 | 0.74 | — | — | |
| SCHEMBL4936842 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535548-B1 | Inhibitor of atherosclerotic intimal thickening | NISSAN CHEMICAL IND LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-6162798-A | Inhibitor of atherosclerotic intimal thickening | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 2000-12-19 | — | — | US | disclosed |
| US-5872130-A | ANTI-HYPERLIPIDEMIC, HYPOLIPOPROTEINEMIC AND ANTI-ATHEROSCLEROTIC AGENTS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| US-5856336-A | Quinoline type mevalonolactones | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| US-5854259-A | Quinoline type mevalonolactones | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1998-12-29 | — | — | US | disclosed |
| EP-0304063-B1 | Quinoline type mevalonolactones | NISSAN CHEMICAL IND LTD (JP) | 1994-11-30 | — | — | EP | disclosed |
| EP-0339358-B1 | Pyrazolopyridine type mevalonolactones | NISSAN CHEMICAL IND LTD (JP) | 1994-07-13 | — | — | EP | disclosed |
| EP-0367235-B1 | Thienopyridine type mevalonolactones | NISSAN CHEMICAL IND LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| EP-0535548-A1 | Inhibitor of atherosclerotic intimal thickening | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5185328-A | Hydroxy-3-methylglutaryl/3-/ coenzyme A reductase inhibitors | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| US-5011930-A | Antilipemic agents, anticoagulants | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1991-04-30 | — | — | US | disclosed |
| US-4977161-A | ANTILIPEMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-12-11 | — | — | US | disclosed |
| WO-1990010624-A1 | PYRIMIDINE TYPE MEVALONOLACTONES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-20 | — | — | WO | disclosed |
| EP-0374448-A1 | Pyrazolopyrimidine type mevalonolactones | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0369323-A1 | Isoxazolopyridine type mevalonolactones | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-05-23 | — | — | EP | disclosed |
| EP-0367235-A1 | Thienopyridine type mevalonolactones | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-05-09 | — | — | EP | disclosed |
| EP-0339358-A1 | Pyrazolopyridine type mevalonolactones | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-11-02 | — | — | EP | disclosed |
| WO-1989010365-A1 | PYRAZOLOPYRIDINE TYPE MEVALONOLACTONES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-02 | — | — | WO | disclosed |
| EP-0308736-A2 | Pyrimidine type mevalonolactones | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-03-29 | — | — | EP | disclosed |
| EP-0304063-A2 | Quinoline type mevalonolactones | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-02-22 | — | — | EP | disclosed |