Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 10/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16005051 | 0.81 | FDPS (0.48) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL16005421 | 0.81 | FDPS (0.48) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL16005396 | 0.81 | FDPS (0.48) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL11557501 | 0.79 | FDPS (0.47) | FDPSSMPD1GGPS1 | |
| SCHEMBL5694480 | 0.78 | FDPS (0.46) | FDPSSMPD1CES2GGPS1 | |
| Hydrochloric Acid SCHEMBL602919 | 0.77 | FDPS (0.45) | FDPSSMPD1GGPS1 | |
| SCHEMBL16005442 | 0.77 | FDPS (0.45) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL16005643 | 0.77 | FDPS (0.45) | FDPSSMPD1CES2GGPS1 | |
| SCHEMBL6281815 | 0.76 | SMPD1 (0.43) | FDPSSMPD1CES2LPAR1LPAR3 | |
| SCHEMBL11603249 | 0.76 | CES2 (0.48) | FDPSCES2LPAR1LPAR3CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115695-A1 | (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(N+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | Monsanto Company (US) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018724-A1 | (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(n+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | disclosed |