Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.62 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicyladehyde SCHEMBL7792796 | 0.90 | TRIM24 (0.50) | TRIM24TRIM33L3MBTL1ERN1CDK4 | |
| Cyclohexylamine SCHEMBL7802599 | 0.79 | KMT2A (0.42) | TRIM24TRIM33LMNAMEN1THRB | |
| Cycloheptanamine SCHEMBL7800205 | 0.79 | KMT2A (0.42) | TRIM24TRIM33LMNAMEN1THRB | |
| Cyclohexylamine SCHEMBL7798049 | 0.79 | MAPT (0.46) | ERN1LMNAMEN1THRBBLM | |
| Salicyladehyde SCHEMBL303535 | 0.79 | TRIM24 (0.90) | TRIM24TRIM33ERN1CDK4CCND1 | |
| Salicyladehyde SCHEMBL28758497 | 0.79 | TRIM24 (0.90) | TRIM24TRIM33ERN1CDK4CCND1 | |
| Salicyladehyde SCHEMBL15395 | 0.79 | — | — | |
| Salicyladehyde SCHEMBL29386538 | 0.79 | — | — | |
| Salicyladehyde SCHEMBL901265 | 0.79 | TRIM24 (1.00) | TRIM24TRIM33ERN1CDK4CCND1 | |
| Salicyladehyde SCHEMBL11675350 | 0.77 | TRIM24 (0.86) | TRIM24TRIM33ERN1CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |