Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924410 | 0.78 | SLC6A2 (0.52) | SLC6A2SLC6A3SLC6A4ANPEPHTR2A | |
| SCHEMBL2115194 | 0.71 | IDO1 (0.44) | RAB9AKMT2A | |
| SCHEMBL30150914 | 0.71 | IDO1 (0.44) | RAB9AKMT2A | |
| SCHEMBL2773405 | 0.68 | ALDH1A1 (0.49) | KMT2A | |
| SCHEMBL8938645 | 0.68 | GAA (0.34) | RAB9AGAAMAPK1KMT2ANPSR1 | |
| SCHEMBL1267589 | 0.67 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4GAAHTR2A | |
| SCHEMBL21694957 | 0.67 | SLC6A2 (0.47) | SLC6A2SLC6A3SLC6A4HTR2A | |
| SCHEMBL8251125 | 0.67 | SLC6A2 (0.47) | SLC6A2SLC6A3SLC6A4HTR2A | |
| SCHEMBL14856038 | 0.67 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4GAAHTR2A | |
| SCHEMBL19774140 | 0.67 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4GAAHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |