Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115194 | 0.89 | IDO1 (0.44) | ALDH1A1KDM4EMEN1KMT2AIDO1 | |
| SCHEMBL30150914 | 0.89 | IDO1 (0.44) | ALDH1A1KDM4EMEN1KMT2AIDO1 | |
| SCHEMBL17495044 | 0.77 | CYP2A6 (0.42) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11079650 | 0.75 | ALDH1A1 (0.34) | ALDH1A1KDM4EMEN1KMT2AIDO1 | |
| SCHEMBL3114732 | 0.75 | HTR2A (0.42) | ALDH1A1KDM4EIDO1 | |
| SCHEMBL6112757 | 0.74 | KDM4E (0.40) | ALDH1A1KDM4EMEN1KMT2AIDO1 | |
| SCHEMBL10643837 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2AIDO1 | |
| SCHEMBL11742887 | 0.73 | TSHR (0.41) | ALDH1A1KDM4EMEN1KMT2AIDO1 | |
| SCHEMBL29024729 | 0.73 | RAB9A (0.46) | ALDH1A1KDM4EMEN1KMT2AIDO1 | |
| SCHEMBL10647055 | 0.73 | HTT (0.44) | ALDH1A1KDM4EMEN1KMT2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1568681-B1 | PROCESS FOR PRODUCING 1,5-DIAMINONAPHTHALENE | MITSUI CHEMICALS INC (JP) | 2010-04-28 | — | — | EP | disclosed |
| EP-1568681-A1 | PROCESS FOR PRODUCING 1,5-DIAMINONAPHTHALENE | Mitsui Chemicals, Inc. (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-6828461-B2 | Process for producing 1,5-diaminonaphthalene | MITSUI CHEMICALS, INC. (JP) | 2004-12-07 | — | — | US | disclosed |
| US-20040143137-A1 | Process for producing 1,5-diaminonaphthalene | MITSUI CHEMICALS, INC. (JP) | 2004-07-22 | — | — | US | disclosed |
| EP-0657427-B1 | Tricyclic indole-2-carboxylic acid derivatives being selective antagonists of the NMDA receptor | SUMITOMO PHARMA (JP) | 2002-06-19 | — | — | EP | disclosed |
| CN-1061034-C | Tricyclic indole-2-carboxylic acid derivatives | SUMITOMO PHARMA (JP) | 2001-01-24 | — | — | CN | disclosed |
| US-5496843-A | Tricyclic indole-2-carboxylic acid derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0657427-A1 | Tricyclic indole-2-carboxylic acid derivatives being selective antagonists of the NMDA receptor | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1995-06-14 | — | — | EP | disclosed |