Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.57 |
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | HTR1D | P28221 | 10/20 | 0.54 |
| ▸ | HTR6 | P50406 | 4/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8035287 | 0.99 | HTR2C (0.56) | HTR2CHTR2AHTR1DHTR6NOS3 | |
| SCHEMBL7798188 | 0.89 | HTR2C (0.54) | HTR2CHTR2AHTR1DHTR6NOS3 | |
| Hydrochloric Acid SCHEMBL8031634 | 0.88 | HTR2C (0.52) | HTR2CHTR2AHTR1DHTR6NOS3 | |
| SCHEMBL7798149 | 0.77 | HTR1D (0.41) | HTR2CHTR2AHTR1DHTR1B | |
| SCHEMBL7808745 | 0.76 | HTR1D (0.43) | HTR2CHTR2AHTR1DHTR6HTR1B | |
| Hydrochloric Acid SCHEMBL8021866 | 0.76 | HTR1D (0.41) | HTR2CHTR2AHTR1DHTR1B | |
| SCHEMBL7805927 | 0.76 | HTR7 (0.50) | HTR1DHTR1B | |
| SCHEMBL23956080 | 0.75 | HTR2C (0.69) | HTR2CHTR2AHTR1DHTR6NOS3 | |
| SCHEMBL1122347 | 0.75 | HTR2C (0.64) | HTR2CHTR2AHTR1DHTR6NOS3 | |
| SCHEMBL7252922 | 0.75 | HTR2A (0.64) | HTR2CHTR2AHTR1DHTR6NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1510034-A | Indazole compound, preparing method thereof and medicine composition containing the same | ɪά��ʵ���� | 2004-07-07 | — | — | CN | claimed |
| CN-1087741-C | Novel indole and indazole compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-07-17 | — | — | CN | claimed |
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | claimed |
| US-6020336-A | Indole and indazole compounds | LES LABORATOIRES SERVIER (FR) | 2000-02-01 | — | — | US | claimed |
| CN-1218052-A | Novel indole and indazole compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-06-02 | — | — | CN | claimed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | claimed |
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |