Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Chloro-Benzoic Acid SCHEMBL7798233 | 1.00 | LTA4H (0.44) | LTA4HTDP1POLBMAPTALDH1A1 | |
| Lysine SCHEMBL7800060 | 0.98 | LTA4H (0.44) | LTA4HTDP1POLBMAPTALDH1A1 | |
| Lysine SCHEMBL7800061 | 0.98 | LTA4H (0.44) | LTA4HTDP1POLBMAPTALDH1A1 | |
| Ornithine SCHEMBL7801382 | 0.94 | LTA4H (0.48) | LTA4HTDP1POLBMAPTALDH1A1 | |
| 4-Chloro-Benzoic Acid SCHEMBL7802524 | 0.92 | CTDSP1 (0.41) | LTA4HTDP1POLBMAPTALDH1A1 | |
| Lysine SCHEMBL7801365 | 0.92 | LTA4H (0.47) | LTA4HTDP1POLBMAPTALDH1A1 | |
| Ornithine Aketoglutarate SCHEMBL7800088 | 0.91 | LTA4H (0.52) | LTA4HTDP1POLBMAPTALDH1A1 | |
| Ornithine SCHEMBL7800091 | 0.91 | LTA4H (0.52) | LTA4HTDP1POLBMAPTALDH1A1 | |
| P-Anisic Acid SCHEMBL7797958 | 0.90 | LTA4H (0.49) | LTA4HTDP1POLBMAPTALDH1A1 | |
| P-Anisic Acid SCHEMBL7797954 | 0.90 | LTA4H (0.49) | LTA4HTDP1POLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |