Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 11/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Anisic Acid SCHEMBL7797954 | 1.00 | LTA4H (0.49) | LTA4HALOX5MTNR1BMTNR1AKMT2A | |
| P-Anisic Acid SCHEMBL7801551 | 0.98 | LTA4H (0.49) | LTA4HALOX5MTNR1BMTNR1AKMT2A | |
| P-Anisic Acid SCHEMBL7801554 | 0.98 | LTA4H (0.49) | LTA4HALOX5MTNR1BMTNR1AKMT2A | |
| Ornithine SCHEMBL7801382 | 0.93 | LTA4H (0.48) | LTA4HPOLBTDP1ALDH1A1MAPT | |
| P-Anisic Acid SCHEMBL7800196 | 0.93 | LTA4H (0.44) | LTA4HMTNR1BMTNR1AKMT2APOLB | |
| Ornithine SCHEMBL7799957 | 0.91 | LTA4H (0.49) | LTA4HALOX5MTNR1BMTNR1AKMT2A | |
| Ornithine Aketoglutarate SCHEMBL7799956 | 0.91 | LTA4H (0.49) | LTA4HALOX5MTNR1BMTNR1AKMT2A | |
| 4-Chloro-Benzoic Acid SCHEMBL7798237 | 0.90 | LTA4H (0.44) | LTA4HPOLBTDP1ALDH1A1MAPT | |
| 4-Chloro-Benzoic Acid SCHEMBL7798233 | 0.90 | LTA4H (0.44) | LTA4HPOLBTDP1ALDH1A1MAPT | |
| P-Anisic Acid SCHEMBL7802573 | 0.90 | LTA4H (0.44) | LTA4HKMT2ATDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |