SCHEMBL7798321

SCHEMBL7798321

O=C(O)/C=C/c1ccccc1C/C=C/c1ccccc1OCc1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 17/20 0.78
PTGER2 P43116 17/20 0.78
PTGER3 P43115 17/20 0.78
PTGER1 P34995 10/20 0.78
PTGDR Q13258 1/20 0.55
CCNB2 O95067 1/20 0.53
CDK1 P06493 1/20 0.53
CDK4 P11802 1/20 0.53
CCNB1 P14635 1/20 0.53
CCND1 P24385 1/20 0.53
CCNB3 Q8WWL7 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7798324 1.00 PTGER4 (0.78) PTGER4PTGER2PTGER3PTGER1PTGDR
SCHEMBL7807158 0.91 PTGER3 (0.75) PTGER4PTGER2PTGER3PTGER1PTGDR
SCHEMBL7807162 0.91 PTGER3 (0.75) PTGER4PTGER2PTGER3PTGER1PTGDR
SCHEMBL7957227 0.90 PTGER4 (0.65) PTGER4PTGER2PTGER3PTGER1PTGDR
SCHEMBL8323200 0.88 PTGER4 (0.94) PTGER4PTGER2PTGER3PTGER1PTGDR
SCHEMBL8323198 0.88 PTGER4 (0.94) PTGER4PTGER2PTGER3PTGER1PTGDR
SCHEMBL7968873 0.83 PTGER4 (0.84) PTGER4PTGER2PTGER3PTGER1PTGDR
SCHEMBL7968870 0.83 PTGER4 (0.84) PTGER4PTGER2PTGER3PTGER1PTGDR
SCHEMBL7955206 0.81 PTGER4 (0.62) PTGER4PTGER2PTGER3PTGER1PTGDR
SCHEMBL8710177 0.79 CCNB2 (0.66) PTGER4PTGER2PTGER3PTGER1CCNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010031766-A1 Prostaglandin receptor ligands MERCK FROSST CANADA & CO. 2001-10-18 US disclosed
EP-1119542-A1 PROSTAGLANDIN RECEPTOR LIGANDS Merck Frosst Canada & Co. (CA) 2001-08-01 EP disclosed
WO-2000020371-A1 PROSTAGLANDIN RECEPTOR LIGANDS MERCK FROSST CANADA & CO. (CA) 2000-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031766-A1 Prostaglandin receptor ligands PTGER1, PTGER2, PTGFR PTGER4 11/4885PTGER2 2/4885PTGER3 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.