Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.84 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.84 |
| ▸ | PTGER3 | P43115 | 8/20 | 0.84 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.84 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.60 |
| ▸ | CDK1 | P06493 | 1/20 | 0.60 |
| ▸ | CDK4 | P11802 | 1/20 | 0.60 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.60 |
| ▸ | CCND1 | P24385 | 1/20 | 0.60 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968870 | 1.00 | PTGER4 (0.84) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL8323198 | 0.94 | PTGER4 (0.94) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL8323200 | 0.94 | PTGER4 (0.94) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL7957928 | 0.89 | PTGER4 (0.67) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL3114346 | 0.83 | PTGER4 (0.74) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL19511288 | 0.83 | PTGER4 (0.74) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL19511064 | 0.83 | PTGER4 (0.74) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL7798324 | 0.83 | PTGER4 (0.78) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL7798321 | 0.83 | PTGER4 (0.78) | PTGER4PTGER2PTGER3PTGER1CCNB2 | |
| SCHEMBL10352269 | 0.82 | PTGER4 (0.74) | PTGER4PTGER2PTGER3PTGER1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031766-A1 | Prostaglandin receptor ligands | MERCK FROSST CANADA & CO. | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031766-A1 | Prostaglandin receptor ligands | PTGER1, PTGER2, PTGFR | PTGER4 11/4885PTGER2 2/4885PTGER3 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.