Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242989 | 0.83 | DNMT1 (0.41) | ALDH1A1HSD17B10HPGDDNMT1KMT2A | |
| SCHEMBL7809844 | 0.81 | KMT2A (0.43) | ALDH1A1HSD17B10CYP1A2THRBHPGD | |
| SCHEMBL29382484 | 0.81 | WDR5 (0.44) | ALDH1A1HSD17B10DNMT1MAPTNPSR1 | |
| SCHEMBL132989 | 0.81 | WDR5 (0.44) | ALDH1A1HSD17B10DNMT1MAPTNPSR1 | |
| SCHEMBL7809791 | 0.81 | MAPT (0.50) | ALDH1A1CYP1A2HPGDKMT2AMEN1 | |
| SCHEMBL9927336 | 0.76 | KDM4E (0.38) | ALDH1A1HSD17B10HPGDDNMT1KMT2A | |
| SCHEMBL18253786 | 0.76 | SOS1 (0.43) | ALDH1A1HSD17B10CYP1A2HPGDKMT2A | |
| SCHEMBL18867021 | 0.75 | DNMT1 (0.39) | ALDH1A1HSD17B10CYP1A2HPGDDNMT1 | |
| SCHEMBL7798373 | 0.75 | TOP1 (0.42) | ALDH1A1HSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL18253736 | 0.75 | CYP1A2 (0.41) | ALDH1A1HSD17B10CYP1A2THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731105-B1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL CO (JP) | 2001-12-05 | — | — | EP | disclosed |
| US-5621129-A | Optically active tertiary phosphine compound, transition metal complex comprising the same as ligand and process for preparing optically active organic silicon compound using said transition metal complex | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0731105-A1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-09-11 | — | — | EP | disclosed |