Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | RRM1 | P23921 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025867 | 0.87 | KMT2A (0.42) | KMT2APOLBAPOBEC3ACASP6CTDSP1 | |
| SCHEMBL7798366 | 0.81 | ALDH1A1 (0.35) | KMT2APOLBAPOBEC3ACASP6CTDSP1 | |
| SCHEMBL132989 | 0.80 | WDR5 (0.44) | POLBMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL29382484 | 0.80 | WDR5 (0.44) | POLBMAPTKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7809791 | 0.80 | MAPT (0.50) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL31171150 | 0.79 | PTPN22 (0.58) | KMT2APOLBMAPTKDM4EPTPN22 | |
| SCHEMBL7796050 | 0.79 | PTPN22 (0.58) | KMT2APOLBMAPTKDM4EPTPN22 | |
| SCHEMBL7118382 | 0.77 | HSP90AA1 (0.42) | KMT2APOLBAPOBEC3ACASP6CTDSP1 | |
| SCHEMBL31296445 | 0.76 | MAPT (0.46) | KMT2APOLBCTDSP1MAPTKDM4E | |
| SCHEMBL7808240 | 0.75 | MAPT (0.51) | KMT2APOLBAPOBEC3ACASP6CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647647-B1 | Tertiary phosphine compound and transition metal complex comprising the same as ligand | SUMITOMO CHEMICAL CO (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5523437-A | Tertiary phosphine compound and transition metal complex comprising the same as ligand | SUMITOMO CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0647647-A1 | Tertiary phosphine compound and transition metal complex comprising the same as ligand | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-04-12 | — | — | EP | disclosed |