Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | ACR | P10323 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797156 | 0.83 | LTA4H (0.39) | LTA4HCHEK2MAPK14MAPTGCGR | |
| SCHEMBL7797160 | 0.83 | LTA4H (0.39) | LTA4HCHEK2MAPK14MAPTGCGR | |
| SCHEMBL6839169 | 0.82 | MAOB (0.63) | MAPTMAOBL3MBTL1 | |
| SCHEMBL7795135 | 0.82 | MAOB (0.63) | MAPTMAOBL3MBTL1 | |
| SCHEMBL6839961 | 0.82 | MAOB (0.63) | MAPTMAOBL3MBTL1 | |
| SCHEMBL7522306 | 0.80 | PTGS1 (0.39) | MAPTMAOB | |
| SCHEMBL7522304 | 0.80 | PTGS1 (0.39) | MAPTMAOB | |
| SCHEMBL7498154 | 0.76 | HIF1A (0.57) | CHEK2MAPK14MAPTGCGRMAOB | |
| SCHEMBL11071994 | 0.75 | MAOB (0.63) | LTA4HCHEK2MAPK14MAPTMAOB | |
| SCHEMBL8182324 | 0.75 | MAPK14 (0.40) | LTA4HCHEK2MAPK14MAPTGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912499-B1 | PESTICIDES | BAYER AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6288071-B1 | FUNGICIDES, INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |
| EP-0912499-A1 | PESTICIDES | Novartis AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997047592-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-12-18 | — | — | WO | disclosed |