Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29726703 | 1.00 | ALDH1A1 (0.52) | ALDH1A1ALOX15KDM4ERAB9AMYC | |
| SCHEMBL36145 | 0.79 | ALDH1A1 (0.72) | ALDH1A1ALOX15KDM4EMYCFOLH1 | |
| SCHEMBL30028907 | 0.79 | ALDH1A1 (0.72) | ALDH1A1ALOX15KDM4EMYCFOLH1 | |
| Hydrochloric Acid SCHEMBL7579852 | 0.77 | ALDH1A1 (0.68) | ALDH1A1ALOX15KDM4EMYCFOLH1 | |
| Hydrochloric Acid SCHEMBL1681943 | 0.77 | ALDH1A1 (0.68) | ALDH1A1ALOX15KDM4EMYCFOLH1 | |
| SCHEMBL28408894 | 0.77 | ALDH1A1 (0.68) | ALDH1A1ALOX15KDM4EMYCFOLH1 | |
| SCHEMBL2830888 | 0.77 | ALDH1A1 (0.68) | ALDH1A1ALOX15KDM4EMYCFOLH1 | |
| Hydrochloric Acid SCHEMBL10888462 | 0.77 | ALDH1A1 (0.68) | ALDH1A1ALOX15KDM4EMYCFOLH1 | |
| SCHEMBL30620175 | 0.77 | ALDH1A1 (0.68) | ALDH1A1ALOX15KDM4EMYCFOLH1 | |
| SCHEMBL9636797 | 0.77 | ALDH1A1 (0.68) | ALDH1A1ALOX15KDM4EMYCFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010027248-A1 | Novel receptor | SMITHKLINE BEECHAM P.L.C. | 2001-10-04 | — | — | US | disclosed |
| US-6245893-B1 | ANTICONVULSANTS, USE IN TREATMENT OR PREVENTION OF NERVOUS SYSTEM DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-06-12 | — | — | US | disclosed |
| US-5985334-A | Screening methods to identify anti-convulsant compounds | SMITHKLINE BEECHAM P.L.C. (GB) | 1999-11-16 | — | — | US | disclosed |
| EP-0807122-A1 | NOVEL RECEPTOR | SMITHKLINE BEECHAM PLC (GB) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996018650-A1 | NOVEL RECEPTOR | SMITHKLINE BEECHAM P.L.C. (GB) | 1996-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010027248-A1 | Novel receptor | ADGRF1, TACR2, GPR4 | ALDH1A1 4099/4885ALOX15 3988/4885KDM4E 4395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.